Partial proteomic analysis of brown widow spider (Latrodectus geometricus) venom to determine the biological activities
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چکیده
منابع مشابه
Neurotoxic activity and ultrastructural changes in muscles caused by the brown widow spider Latrodectus geometricus venom.
Brown widow spider (Latrodectus geometricus) venom (BrWSV) produces few local lesions and intense systemic reactions such as cramps, harsh muscle pains, nausea, vomiting and hypertension. Approximately 16 protein bands under reducing conditions and approximately 14 bands under non-reducing conditions on a 12.5% sodium dodecyl sulfate-polyacrylamide gel electrophoresis were observed. Neurotoxic ...
متن کاملFirst record of a brown widow spider Latrodectus geometricus Koch, 1841 (Araneae, Theridiidae) feeding scorpion (Scorpiones, Bothriuridae) in a Brazilian Atlantic forest.
Scorpions are generalist predators, capturing a great variety of arthropods including even small vertebrates (Polis, 1990), however, they are also subject to predation, especially by vertebrates such as amphibians, reptiles, birds and mammals (Polis et al., 1981; McCormick and Polis, 1990). Regarding the invertebrates, there are reports of predation by coleopterans, chilopods, solpugids, others...
متن کاملBrown Spider (Loxosceles genus) Venom Toxins: Tools for Biological Purposes
Venomous animals use their venoms as tools for defense or predation. These venoms are complex mixtures, mainly enriched of proteic toxins or peptides with several, and different, biological activities. In general, spider venom is rich in biologically active molecules that are useful in experimental protocols for pharmacology, biochemistry, cell biology and immunology, as well as putative tools ...
متن کاملBrown recluse spider venom: proteomic analysis and proposal of a putative mechanism of action.
Loxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage to the toxin structures.
متن کاملDevelopment of Latrodectus Envenomation Severity Score (LESS); a Severity Index for Widow Spider Bite: Initial Step
Background: In order to describe the patients and evaluate the effectiveness of treatments for widow spider envenomation, investigators require a reliable assessment tool. In this paper, the development of a clinical index for measuring the widow spider bite severity, Latrodectus Envenomation Severity Score (LESS), is described. Methods: According to the valid methods for index development, a D...
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ژورنال
عنوان ژورنال: Toxicon: X
سال: 2020
ISSN: 2590-1710
DOI: 10.1016/j.toxcx.2020.100062